What You Need to Know About GLP-1 Receptor Agonist Storage Instructions
Proper storage and handling are crucial for maintaining the potency and integrity of glucagon-like peptide-1 (GLP-1) receptor agonists, including semaglutide, dulaglutide, liraglutide, and tirzepatide.
Room Temperature vs. Refrigeration: What's the Difference?
The duration and conditions under which GLP-1 receptor agonists can be stored at room temperature vary between products. For example, Novo Nordisk GLP-1 RA products such as Ozempic, Rybelsus, Wegovy, Saxenda, and Victoza allow for specific periods of storage at room temperature after opening before use, according to their FDA labeling.
Storing GLP-1 Receptor Agonist Prefilled Pens:
- Unused pens should be stored in the original box in the medication fridge at 2 to 8o C until the manufacturer's expiry date.
Factors to Consider for Proper Storage:

- Medications like Ozempic, Wegovy, Mounjaro, Zepbound, Saxenda, and other GLP-1 receptor agonists should be refrigerated until first use. However, some products permit limited room temperature storage.
Beyond Standard Storage Guidelines:
- Some GLP-1 receptor agonists allow multi-dose pens to be stored at room temperature after opening.
Understanding proper storage and handling for GLP-1 receptor agonists ensures medication effectiveness while maintaining potency throughout its shelf life.